Other studies have found that diets rich in blueberries significantly improved both the learning capacity and motor skills of aging animals, making them mentally equivalent to animals much younger.

Based on data from the USDA Human Nutrition Research Center on Aging (Boston, MA), blueberries are among the fruits with the highest antioxidant activity.

Researchers have shown that blueberry anthocyanins, proanthocyanidins, resveratrol, flavonols, and tannins inhibit cancer cell development and inflammation in vitro.  Similar to red grapes, some blueberry species contain significant levels of resveratrol in their skins.

Another study suggests that the best way to gain maximum benefits from blueberries and other fruits eaten for their polyphenol content is to consume them either one hour before protein is consumed, or two hours after.
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In one study, Jim Joseph, director of the neuroscience laboratory in the USDA Human Nutrition Research Center (HNRC), fed blueberry extractions—the equivalent of a human eating one cup of blueberries a day—to mice and then ran them through a series of motor skills tests.
He found that the blueberry-fed mice performed better than their control group counterparts in motor behavioral learning and memory, and he noticed an increase in exploratory behavior.

Other studies have found that diets rich in blueberries significantly improved both the learning capacity and motor skills of aging animals, making them mentally equivalent to animals much younger.

Rats were fed a diet that included a non-steroidal anti-inflammatory drug (NSAID), or a 2 percent blueberry diet. After two weeks and behavioral evaluation, the rats were examined. The researchers found the blueberry diet was able to improve cognitive performance to a much greater degree than  the NSAID diet. Blueberry eaters showed a reduction in several factors influencing the inflammatory response. They concluded that blueberry polyphenols reduced inflammation and can lessen learning impairments resulting from neurotoxic damage .

Another study suggests that the best way to gain maximum benefits from blueberries and other fruits eaten for their polyphenol content is to consume them either one hour before protein is consumed, or two hours after.
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